Single-molecule and super-resolution microscopy at the University of Edinburgh.

The Edinburgh Single-Molecule Biophysics (ESMB) Group started at the University of Edinburgh in 2018. 
Headed by Mathew Horrocks, we are based in the School of Chemistry, and the Dementia Research Institute, at the University of Edinburgh. We use physical chemistry to understand the biological processes associated with disease. In particular, we are interested in developing and using fluorescence-based single-molecule and super-resolution methods to understand neurodegenerative disorders, such as Alzheimer's and Parkinson's disease. For more information on our research, please visit our Research page.

The national UK Dementia Research Institute (UK DRI) is the single biggest investment in dementia research in the UK. Established in 2017 by the Medical Research Council, Alzheimer’s Society and Alzheimer’s Research UK, the £250million institute is located across six leading UK universities: University of Cambridge, Cardiff University, University of Edinburgh, Imperial College London and King’s College London, with its central hub at UCL. The UK DRI will accelerate discoveries to prevent, treat and care for people with all types of dementia, and it will help us understand ways to keep the brain healthy. The UK DRI attracts the brightest minds in research, both in the UK and globally, and will be made up of over 400 researchers, continuing to make the UK one of the best places in the world to study neuroscience. More info:


School of Chemistry
Joseph Black Building
David Brewster Rd


Phone: 0131 6504787 (Chemistry). 
0131 2426251 (UK DRI).