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A range of new fluorophores for imaging metabolites in live cells

posted Apr 3, 2019, 3:11 AM by Mathew Horrocks
We're excited that our work with Dr. Marc Vendrell and the Dynafluors group has been published in Angewandte Chemie. The work describes a new class of fluorophores that can be used to tag metabolites for imaging in live cells. In the work, we used TIRF microscopy to image lactate within normal and hypoxic cells. Single particle tracking enabled the diffusion co-efficients of the lactate to be measured.